Inside the Lining: Endometrial Biopsy What is an Endometrial Biopsy? An endometrial biopsy is a medical procedure in which a small sample of the lining of the uterus (the endometrium) is removed for microscopic examination. This tissue sample allows pathologists to look for abnormal cells, hormonal imbalances, or signs of infection that cannot be seen on an ultrasound. The procedure is typically performed in an outpatient setting without the need for general anesthesia. A very thin, flexible tube called a Pipelle is inserted through the natural opening of the cervix into the uterine cavity. Using gentle suction, a small amount of tissue is collected. The entire process usually takes less than ten minutes. Why is this Procedure Personally Vital for You? An endometrial biopsy provides definitive tissue-level evidence to explain uterine symptoms. This pathway is personally vital for you if: You Experience Abnormal Uterine Bleeding: If you have heavy periods, bleeding between cycles, or irregular spotting, a biopsy helps determine if the cause is hormonal or structural. Post-Menopausal Bleeding Occurs: Any bleeding after menopause is a clinical priority. A biopsy is the primary method used to rule out endometrial hyperplasia or uterine cancer. Monitoring During Hormone Therapy: If you are taking Tamoxifen or Hormone Replacement Therapy (HRT), periodic biopsies ensure the uterine lining remains healthy and thin. Infertility Investigations: For those struggling to conceive, a biopsy can check if the lining is properly responding to hormones and is "receptive" for an embryo to implant. The Path to Diagnostic Clarity and Stability The goal of this procedure is to obtain a clear "snapshot" of your uterine health while ensuring your systemic stability. This pathway is designed to: Provide Pathological Precision: By analyzing the cells directly, our medical board can move beyond "suspected" diagnoses to confirmed, data-driven treatment plans. Ensure Clinical Readiness through Rigorous Screening: To ensure the procedure is safe and timed correctly, we require a full medical history, diagnostic X-rays (specifically a chest X-ray for surgical clearance), and comprehensive blood tests (including pregnancy tests, coagulation profiles to manage bleeding risks, and full blood counts). A Focused Recovery and Stabilization Window: Although the procedure is brief, the uterine lining is a sensitive and highly vascular tissue. We focus on a 2–3 week recovery and stabilization period. This window is essential for the cervix to close completely after the instrument''s passage, for any cramping or spotting to subside, and to allow the pathology lab to provide a definitive report while your body resets its natural cycle. All details are subject to doctor evaluation for the final treatment plan.